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GLP 1 drug Liraglutide may protect against dementia GLP 1 in addiction medicine: GLP 1 acts on pancreas, gut, kidney, heart and thyroid receptors to activate reward stress hubs (VTA, NAc, ARC, PFC, hypothalamus). GLP 1 RAs provide sustained central Scott Isaacs, MD, Codeage GLP 1 Probiotic+, Live Probiotics Akkermansia, Clostridium & Bifidobacterium, Chicory Bloomingdale's Beauty & Cosmetics What to Expect When Switching From a Compounded GLP 1 to a Branded Option Glucagon like peptide 1 receptor agonists (GLP 1RAs) have become increasingly popular for the management of obesity and diabetes. You know these drugs by names like semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro, Zepbound), and liraglutide (Saxenda,
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4.3 ★★★★★
Based on 62 reviews
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Product Reviews
★★★★★ 5
Worthwhile!
Size: Medium/Large, Color: Turkey Day Drumstick - Large
I have a small dog with a really strong bite! Usually have to buy toys that are meant for bigger dogs. This has lasted us for what feels like forever. It does sound very heavy when dropped! My dog loves it though! Would definitely recommend!
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Reviewed in the United States on May 2, 2026
★★★★★ 5
Ohhh Mr. Iguana
Size: Medium/Large, Color: Illana the Iguana - Large
Mr. Iguana is a house favorite! I got my first one of these in a barkbox and my dog loved it so much, i went on the hunt for another one. Amazon saved the day! I own about 7 of these now. They are prefect for dogs just love to chew, they hold up great! And they are heavy duty, super easy to clean! My dogs are very happy, great value for the money! Doesn't have a smell, vibrant colors! Noise level is quiet, minus my dogs chewing !
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Reviewed in the United States on August 13, 2025
★★★★★ 3
Not for strong chewers
Size: Medium/Large, Color: Dog Ness Monster - Large
Initially, I really liked this for my dog. She is about 8 months old and still loves to chew and destroys most toys in a few minutes. When we got this, it seemed like it would hold up for a while despite being clearly gnawed on. Unfortunately, once she focused on the softer "water" portion of the toy, that is where things went downhill with this toy. After a few short chew sessions, she was tearing chunks out of it. We had purchased a replacement since she liked the original so much, and after about 5 minutes with the replacement, she had taken enough out of the blue section that we immediately threw that one out as well. Overall while the green portion held up, the blue didn't. I can't recommend this for strong chewers.
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Reviewed in the United States on December 8, 2025
★★★★★ 4
Definitely not indestructable
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
I have a 1-year-old toy fox terrier (Rocky, pictured). He has been chewing on this toy for seven months now; it is one of his favorites. He has been unable to seriously damage the "ocean" portion of this toy, but as you can see from the provided image, the sea serpent has not faired that well. It is missing its snout and smaller portions of the humps. My guess is that the advertiser images showing much larger dogs with "like new" versions of the toy are just that...NEW AND UNCHEWED.
I have not had to clean up bits of this toy from my floor, so I assume Rocky has been swallowing them. My hope is that the yellow material of the serpent is not chemically dangerous when exposed to digestive fluids.
Rocky easily destroys plush toys in a matter of days if not hours and, consumed pieces of a small microfiber blanket that he liked to toss around and play tug-of-war with (past tense as he destroyed it and has since been trashed after I began finding feces-stained undigested pieces of it lying around). Since this toy has survived seven months and has remained recognizable, I have to agree it is durable.
Just beware, if my small toy fox terrier can damage the toy as pictured, expect your large breed chewer to do similar or worse damage. Also, the toy is very heavy! When Rocky drops it down a flight of stairs, it makes a MAJOR thud at the bottom, and sometimes makes me wonder if it might crack the large tile at the bottom.
I cautiously recommend the product.
Note the yellow frisbee in Rocky's picture. It is only a few months old and surprisingly has not suffered any chew damage despite substantial abuse. It appears to bend in the wind like a proverbial reed, evading damage by yielding to pressure.
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Reviewed in the United States on July 5, 2024
★★★★★ 5
Dog loves it! For tough chewers for sure
Size: Medium/Large, Color: Dog Ness Monster - Large, Size: Medium/Large, Color: Dog Ness Monster - Large
Dog absolutely loves it, he’s super rough on all of his toys they usually last about 10 minutes bore they are torn to shreds. It’s lasting through his chewing so I’m happy. It’s also super cute.
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Reviewed in the United States on April 9, 2026
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