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Before you grab the tums, heres a few things that can help with GI distress (including reflux and heart burn) from GLP 1 medicines:, 1. Eat smaller meals and lower fat intake. You dont have to do The GLP 1 Bulge: Is Bloating a Normal Side Effect? GLP 1 Gut Support Pack JumpstartMD GLP Weight Loss Medications Compounded GLP Injections GLP 1 Users Often Restart Medication After Stopping, Finds Study; What Exactly Happens After Quitting?